Severe dry eye associated with Steven Johnson Syndrome: A case report

Case Report

Author Details : Namrata Shree*, Baby Deka, Rajneel Bhattacharjee

Volume : 7, Issue : 2, Year : 2021

Article Page : 225-228

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Introduction: Stevens-Johnson-Syndrome (SJS), and its severe variant, toxic epidermal necrolysis (TEN), are life-threatening diseases of skin and mucous membranes. Cases with pseudo-membrane formation and epithelial defects, have higher risk of ocular sequelae. Severe dry eye in SJS includes three mechanisms: (1) aqueous tear deficiency, (2) decreased wettability of corneal surface, and (3) increased evaporation.
Observation: A 47-year-old male patient presented in OPD with chief complaint of severe discomfort and grittiness in both eyes since last 21 years. Proper history taking and examination was done. Patient was given conservative treatment and was explained about recent advancements of treatment that can help in improving his condition.
Conclusion : In SJS patients, dryness causes eye pain, and unstable tear film causes diminution of vision. After acute stage reactions, visual impairment and severe dry eye are observed as ocular sequelae.
Keywords : Case Report, Dry eye, Steven Johnson Syndrome, Toxic Epidermal Necrolysis

How to cite : Shree N, Deka B, Bhattacharjee R, Severe dry eye associated with Steven Johnson Syndrome: A case report. IP Int J Ocul Oncol Oculoplasty 2021;7(2):225-228

Copyright © 2021 by author(s) and IP Int J Ocul Oncol Oculoplasty. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (

Article History

Received : 04-06-2021

Accepted : 16-06-2021

Available online : 24-07-2021

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